U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hypoechoic breast mass

MedGen UID:
1052406
•Concept ID:
CN377462
•
Finding
Synonym: Hypoechoic breast nodule
 
HPO: HP:6000630

Definition

A breast mass visualized by sonography that displays a lower than normal echo signal (and this that appears dark gray in the typical ultrasound image). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHypoechoic breast mass

Professional guidelines

PubMed

Mammary and extramammary myofibroblastoma: multimodality imaging features with clinicopathologic correlation, management and outcomes in a series of 23 patients.
Wickre M, Valencia E, Solanki M, Glazebrook K
Br J Radiol 2021 Apr 1;94(1120):20201019. Epub 2020 Dec 17 doi: 10.1259/bjr.20201019. PMID: 33332985Free PMC Article
Diagnosis and Treatment of 75 Patients with Idiopathic Lobular Granulomatous Mastitis.
Li J
J Invest Surg 2019 Aug;32(5):414-420. Epub 2018 Jan 30 doi: 10.1080/08941939.2018.1424270. PMID: 29381437
The diagnosis and management of diabetic mastopathy.
Thorncroft K, Forsyth L, Desmond S, Audisio RA
Breast J 2007 Nov-Dec;13(6):607-13. doi: 10.1111/j.1524-4741.2007.00489.x. PMID: 17983405

Recent clinical studies

Etiology

Beyond BI-RADS: Nonmass Abnormalities on Breast Ultrasound.
Tsunoda H, Moon WK
Korean J Radiol 2024 Feb;25(2):134-145. Epub 2024 Jan 10 doi: 10.3348/kjr.2023.0769. PMID: 38238012Free PMC Article
Tubular Adenoma of the Breast: Radiologic-Pathologic Correlation.
Joo GJ, Carter GJ, Berg WA
J Breast Imaging 2023 Nov 30;5(6):703-711. doi: 10.1093/jbi/wbad066. PMID: 38141235
Incidental DCIS within a fibroadenoma.
Chen A, Kanakaratne S, Britten-Jones P, Bingham J
BMJ Case Rep 2023 Sep 26;16(9) doi: 10.1136/bcr-2023-254609. PMID: 37751969Free PMC Article
Imaging Challenges in Diagnosing Triple-Negative Breast Cancer.
Schopp JG, Polat DS, Arjmandi F, Hayes JC, Ahn RW, Sullivan K, Sahoo S, Porembka JH
Radiographics 2023 Oct;43(10):e230027. doi: 10.1148/rg.230027. PMID: 37708071
Gestational breast cancer.
Samuels TH, Liu FF, Yaffe M, Haider M
Can Assoc Radiol J 1998 Jun;49(3):172-80. PMID: 9640283

Diagnosis

Mixed and Purely Hyperechoic Breast Masses: A Radiologic-Pathologic Review.
Chesebro AL, Joseph S, Kuba MG, Lester S, Giess CS
J Breast Imaging 2023 Feb 6;5(1):85-92. doi: 10.1093/jbi/wbac079. PMID: 38416961
Myeloid Sarcoma of the Breast: A Diagnostic Dilemma With Pathologic Correlation.
Hsu J, Factor R, Lowell DA, Sobolewski R, Ghate SV
J Breast Imaging 2023 Jul 28;5(4):459-466. doi: 10.1093/jbi/wbad019. PMID: 38416899
Primary and Secondary Breast Lymphoma: Clinical, Pathologic, and Multimodality Imaging Review.
Raj SD, Shurafa M, Shah Z, Raj KM, Fishman MDC, Dialani VM
Radiographics 2019 May-Jun;39(3):610-625. Epub 2019 Mar 29 doi: 10.1148/rg.2019180097. PMID: 30924754
Myofibroblastoma of the breast.
Shanmugasiva VV, Ramli Hamid MT, Fadzli F, Shaleen Kaur KS, Abd Rahman N, Rahmat K
Malays J Pathol 2018 Dec;40(3):349-353. PMID: 30580368
Granulomatous mastitis.
Diesing D, Axt-Fliedner R, Hornung D, Weiss JM, Diedrich K, Friedrich M
Arch Gynecol Obstet 2004 May;269(4):233-6. Epub 2003 Dec 19 doi: 10.1007/s00404-003-0561-2. PMID: 15205978

Therapy

Primary and Secondary Breast Lymphoma: Clinical, Pathologic, and Multimodality Imaging Review.
Raj SD, Shurafa M, Shah Z, Raj KM, Fishman MDC, Dialani VM
Radiographics 2019 May-Jun;39(3):610-625. Epub 2019 Mar 29 doi: 10.1148/rg.2019180097. PMID: 30924754
Imaging Features Associated With Posttraumatic Breast Neuromas.
AlSharif S, Ferré R, Omeroglu A, El Khoury M, Mesurolle B
AJR Am J Roentgenol 2016 Mar;206(3):660-5. doi: 10.2214/AJR.14.14035. PMID: 26901025
Gynecomastia caused by ethionamide.
Sharma PK, Bansal R
Indian J Pharmacol 2012 Sep-Oct;44(5):654-5. doi: 10.4103/0253-7613.100408. PMID: 23112434Free PMC Article
A case of ectopic breast cancer with a literature review.
Nihon-Yanagi Y, Ueda T, Kameda N, Okazumi S
Surg Oncol 2011 Mar;20(1):35-42. Epub 2009 Oct 22 doi: 10.1016/j.suronc.2009.09.005. PMID: 19853438
Granulomatous mastitis.
Diesing D, Axt-Fliedner R, Hornung D, Weiss JM, Diedrich K, Friedrich M
Arch Gynecol Obstet 2004 May;269(4):233-6. Epub 2003 Dec 19 doi: 10.1007/s00404-003-0561-2. PMID: 15205978

Prognosis

Tubular Adenoma of the Breast: Radiologic-Pathologic Correlation.
Joo GJ, Carter GJ, Berg WA
J Breast Imaging 2023 Nov 30;5(6):703-711. doi: 10.1093/jbi/wbad066. PMID: 38141235
Clinical and sonographic features of nipple lesions.
Cai S, Wang H, Zhu Q, Li J, Sun Q, Jiang Y
Medicine (Baltimore) 2020 Apr;99(15):e19728. doi: 10.1097/MD.0000000000019728. PMID: 32282731Free PMC Article
Non-mass-like lesions on breast ultrasound: classification and correlation with histology.
Wang ZL, Li N, Li M, Wan WB
Radiol Med 2015 Oct;120(10):905-10. Epub 2015 Mar 1 doi: 10.1007/s11547-014-0493-x. PMID: 25725790
US appearance of ductal carcinoma in situ.
Wang LC, Sullivan M, Du H, Feldman MI, Mendelson EB
Radiographics 2013 Jan-Feb;33(1):213-28. doi: 10.1148/rg.331125092. PMID: 23322838
Intramammary lymph nodes: a question seeking for an answer or an answer seeking for a question?
Troupis T, Michalinos A, Skandalakis P
Breast 2012 Oct;21(5):615-20. Epub 2012 Jun 29 doi: 10.1016/j.breast.2012.06.006. PMID: 22749923

Clinical prediction guides

Granulomatous Mastitis: A Clinical and Diagnostic Dilemma.
Pala EE, Ekmekci S, Kilic M, Dursun A, Colakoglu G, Karaali C, Emiroglu M, Emiroglu M
Turk Patoloji Derg 2022;38(1):40-45. doi: 10.5146/tjpath.2021.01554. PMID: 34558655Free PMC Article
Clinicopathological and Imaging Features Predictive of Clinical Outcome in Metaplastic Breast Cancer.
Yoon GY, Cha JH, Kim HH, Shin HJ, Chae EY, Choi WJ, Oh HY
Curr Med Imaging 2020;16(6):729-738. doi: 10.2174/1573405615666190219105810. PMID: 32723245
Clinical and sonographic features of nipple lesions.
Cai S, Wang H, Zhu Q, Li J, Sun Q, Jiang Y
Medicine (Baltimore) 2020 Apr;99(15):e19728. doi: 10.1097/MD.0000000000019728. PMID: 32282731Free PMC Article
Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings.
Barreto DS, Sedgwick EL, Nagi CS, Benveniste AP
Breast Cancer Res Treat 2018 Oct;171(3):527-534. Epub 2018 Jul 3 doi: 10.1007/s10549-018-4870-3. PMID: 29971624
Non-mass-like lesions on breast ultrasound: classification and correlation with histology.
Wang ZL, Li N, Li M, Wan WB
Radiol Med 2015 Oct;120(10):905-10. Epub 2015 Mar 1 doi: 10.1007/s11547-014-0493-x. PMID: 25725790

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...