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Furcation Defects

MedGen UID:
104829
•Concept ID:
C0206306
•
Pathologic Function
Synonyms: Defect, Furcation; Defects, Furcation; Furcation Defect

Definition

Conditions in which a bifurcation or trifurcation of the molar tooth root becomes denuded as a result of periodontal disease. It may be followed by tooth mobility, temperature sensitivity, pain, and alveolar bone resorption. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFurcation Defects

Professional guidelines

PubMed

Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.
Chatzopoulos GS, Koidou VP, Tsalikis L
Clin Oral Investig 2023 Mar;27(3):955-970. Epub 2023 Feb 2 doi: 10.1007/s00784-023-04871-0. PMID: 36729235Free PMC Article
Management of Furcation-Involved Molars: Recommendation for Treatment and Regeneration.
Rasperini G, Majzoub J, Tavelli L, Limiroli E, Katayama A, Barootchi S, Hill R, Wang HL
Int J Periodontics Restorative Dent 2020 Jul/Aug;40(4):e137-e146. doi: 10.11607/prd.4341. PMID: 32559031
Using Enamel Matrix Derivative to Improve Treatment Efficacy in Periodontal Furcation Defects.
Masaeli R, Zandsalimi K, Lotfi Z, Tayebi L
J Prosthodont 2018 Oct;27(8):733-736. Epub 2018 Jan 11 doi: 10.1111/jopr.12753. PMID: 29322600

Recent clinical studies

Etiology

Complications and treatment errors related to regenerative periodontal surgery.
Jepsen K, Sculean A, Jepsen S
Periodontol 2000 2023 Jun;92(1):120-134. Epub 2023 Jul 12 doi: 10.1111/prd.12504. PMID: 37435999
Resective surgery for the treatment of furcation involvement: A systematic review.
Dommisch H, Walter C, Dannewitz B, Eickholz P
J Clin Periodontol 2020 Jul;47 Suppl 22:375-391. doi: 10.1111/jcpe.13241. PMID: 31912534
Regenerative surgical treatment of furcation defects: A systematic review and Bayesian network meta-analysis of randomized clinical trials.
Jepsen S, Gennai S, Hirschfeld J, Kalemaj Z, Buti J, Graziani F
J Clin Periodontol 2020 Jul;47 Suppl 22:352-374. doi: 10.1111/jcpe.13238. PMID: 31860125
Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):666-74. doi: 10.1902/jop.1996.67.7.666. PMID: 8832477
Prognosis versus actual outcome. II. The effectiveness of clinical parameters in developing an accurate prognosis.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):658-65. doi: 10.1902/jop.1996.67.7.658. PMID: 8832476

Diagnosis

A novel decision-making process for tooth retention or extraction.
Avila G, Galindo-Moreno P, Soehren S, Misch CE, Morelli T, Wang HL
J Periodontol 2009 Mar;80(3):476-91. doi: 10.1902/jop.2009.080454. PMID: 19254132
Diagnosis and epidemiology of periodontal osseous lesions.
Papapanou PN, Tonetti MS
Periodontol 2000 2000 Feb;22:8-21. doi: 10.1034/j.1600-0757.2000.2220102.x. PMID: 11276518
Furcation diagnosis.
Müller HP, Eger T
J Clin Periodontol 1999 Aug;26(8):485-98. doi: 10.1034/j.1600-051x.1999.260801.x. PMID: 10450808
Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):666-74. doi: 10.1902/jop.1996.67.7.666. PMID: 8832477
Prognosis versus actual outcome. II. The effectiveness of clinical parameters in developing an accurate prognosis.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):658-65. doi: 10.1902/jop.1996.67.7.658. PMID: 8832476

Therapy

Resective surgery for the treatment of furcation involvement: A systematic review.
Dommisch H, Walter C, Dannewitz B, Eickholz P
J Clin Periodontol 2020 Jul;47 Suppl 22:375-391. doi: 10.1111/jcpe.13241. PMID: 31912534
Regenerative surgical treatment of furcation defects: A systematic review and Bayesian network meta-analysis of randomized clinical trials.
Jepsen S, Gennai S, Hirschfeld J, Kalemaj Z, Buti J, Graziani F
J Clin Periodontol 2020 Jul;47 Suppl 22:352-374. doi: 10.1111/jcpe.13238. PMID: 31860125
Periodontal regeneration.
Ivanovski S
Aust Dent J 2009 Sep;54 Suppl 1:S118-28. doi: 10.1111/j.1834-7819.2009.01150.x. PMID: 19737264
A novel decision-making process for tooth retention or extraction.
Avila G, Galindo-Moreno P, Soehren S, Misch CE, Morelli T, Wang HL
J Periodontol 2009 Mar;80(3):476-91. doi: 10.1902/jop.2009.080454. PMID: 19254132
Regenerative therapy: furcation defects.
Karring T, Cortellini P
Periodontol 2000 1999 Feb;19:115-37. doi: 10.1111/j.1600-0757.1999.tb00151.x. PMID: 10321220

Prognosis

Complications and treatment errors related to regenerative periodontal surgery.
Jepsen K, Sculean A, Jepsen S
Periodontol 2000 2023 Jun;92(1):120-134. Epub 2023 Jul 12 doi: 10.1111/prd.12504. PMID: 37435999
Management of Furcation-Involved Molars: Recommendation for Treatment and Regeneration.
Rasperini G, Majzoub J, Tavelli L, Limiroli E, Katayama A, Barootchi S, Hill R, Wang HL
Int J Periodontics Restorative Dent 2020 Jul/Aug;40(4):e137-e146. doi: 10.11607/prd.4341. PMID: 32559031
Furcation diagnosis.
Müller HP, Eger T
J Clin Periodontol 1999 Aug;26(8):485-98. doi: 10.1034/j.1600-051x.1999.260801.x. PMID: 10450808
Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):666-74. doi: 10.1902/jop.1996.67.7.666. PMID: 8832477
Prognosis versus actual outcome. II. The effectiveness of clinical parameters in developing an accurate prognosis.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):658-65. doi: 10.1902/jop.1996.67.7.658. PMID: 8832476

Clinical prediction guides

Periodontal regeneration.
Ivanovski S
Aust Dent J 2009 Sep;54 Suppl 1:S118-28. doi: 10.1111/j.1834-7819.2009.01150.x. PMID: 19737264
Influence of residual pockets on progression of periodontitis and tooth loss: results after 11 years of maintenance.
Matuliene G, Pjetursson BE, Salvi GE, Schmidlin K, Brägger U, Zwahlen M, Lang NP
J Clin Periodontol 2008 Aug;35(8):685-95. Epub 2008 Jul 23 doi: 10.1111/j.1600-051X.2008.01245.x. PMID: 18549447
Furcation diagnosis.
Müller HP, Eger T
J Clin Periodontol 1999 Aug;26(8):485-98. doi: 10.1034/j.1600-051x.1999.260801.x. PMID: 10450808
Prognosis versus actual outcome. III. The effectiveness of clinical parameters in accurately predicting tooth survival.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):666-74. doi: 10.1902/jop.1996.67.7.666. PMID: 8832477
Prognosis versus actual outcome. II. The effectiveness of clinical parameters in developing an accurate prognosis.
McGuire MK, Nunn ME
J Periodontol 1996 Jul;67(7):658-65. doi: 10.1902/jop.1996.67.7.658. PMID: 8832476

Recent systematic reviews

Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.
Chatzopoulos GS, Koidou VP, Tsalikis L
Clin Oral Investig 2023 Mar;27(3):955-970. Epub 2023 Feb 2 doi: 10.1007/s00784-023-04871-0. PMID: 36729235Free PMC Article
Chorion and amnion/chorion membranes in oral and periodontal surgery: A systematic review.
Gulameabasse S, Gindraux F, Catros S, Fricain JC, Fenelon M
J Biomed Mater Res B Appl Biomater 2021 Aug;109(8):1216-1229. Epub 2020 Dec 22 doi: 10.1002/jbm.b.34783. PMID: 33354857
Resective surgery for the treatment of furcation involvement: A systematic review.
Dommisch H, Walter C, Dannewitz B, Eickholz P
J Clin Periodontol 2020 Jul;47 Suppl 22:375-391. doi: 10.1111/jcpe.13241. PMID: 31912534
Regenerative surgical treatment of furcation defects: A systematic review and Bayesian network meta-analysis of randomized clinical trials.
Jepsen S, Gennai S, Hirschfeld J, Kalemaj Z, Buti J, Graziani F
J Clin Periodontol 2020 Jul;47 Suppl 22:352-374. doi: 10.1111/jcpe.13238. PMID: 31860125
Periodontal regeneration - furcation defects: a systematic review from the AAP Regeneration Workshop.
Avila-Ortiz G, De Buitrago JG, Reddy MS
J Periodontol 2015 Feb;86(2 Suppl):S108-30. doi: 10.1902/jop.2015.130677. PMID: 25644295

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