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TPMT genotyping
Clinical Genetic Test
Help
offered by
Sinochips Diagnostics
GTR Test Accession: Help GTR000592433.1
PHARMACOGENOMICINHERITED DISEASEMETABOLIC DISEASE ... View more
Registered in GTR: 2021-02-15
View version history
Last annual review date for the lab: 2024-07-15 LinkOut
At a Glance
Test purpose: Help
Drug Response; Monitoring; Risk Assessment; ...
Conditions (4): Help
Thiopurine S-methyltransferase deficiency; Azathioprine response; Mercaptopurine response more...
Genes (1): Help
TPMT (6p22.3)
Methods (1): Help
Molecular Genetics - Targeted variant analysis: RT-PCR
Target population: Help
Not provided
Clinical validity: Help
Not provided
Clinical utility: Help
Not provided
Ordering Information
Offered by: Help
Sinochips Diagnostics
View lab's website
Test short name: Help
TPMT
Specimen Source: Help
  • Buccal swab
  • Peripheral (whole) blood
  • Plasma
  • Saliva
Who can order: Help
  • Genetic Counselor
  • Health Care Provider
  • In-State Patients
  • Licensed Physician
  • Nurse Practitioner
  • Out-of-State Patients
  • Physician Assistant
  • Public Health Mandate
  • Registered Nurse
Contact Policy: Help
Laboratory can only accept contact from health care providers. Patients/families are encouraged to discuss genetic testing options with their health care provider.
How to Order: Help
Please fill in the contact form at https://sinochipsdiagnostics.com/contact/ or give us a call (877) 746-6244.
Order URL
Test development: Help
Test developed by laboratory but exempt from FDA oversight (eg. NYS CLEP approved, offered within a hospital or clinic)
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Test Order Code, Lab contact for this test, Test strategy
Conditions Help
Total conditions: 4
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 1
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 1
Method Category Help
Test method Help
Instrument *
Targeted variant analysis
RT-PCR
* Instrument: Not provided
Clinical Information
Test purpose: Help
Drug Response; Monitoring; Risk Assessment; Therapeutic management
Recommended fields not provided:
Clinical validity, Clinical utility, Target population, What is the protocol for interpreting a variation as a VUS?, Are family members with defined clinical status recruited to assess significance of VUS without charge?, Will the lab re-contact the ordering physician if variant interpretation changes?, Is research allowed on the sample after clinical testing is complete?, Sample negative report, Sample positive report
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
Accuracy 97.4%; analytical Sensitivity 3.1 ng/uL; precision 96.7%
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Test Confirmation, Assay limitations, Description of internal test validation method, Citations for Analytical validity, PT Provider, Description of PT method, Major CAP category, CAP category, CAP test list
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

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