Hereditary High Risk Breast Cancer Panel
Clinical Genetic Test
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offered by
GTR Test Accession: Help GTR000553676.3
INHERITED DISEASECANCERINHERITED DISEASE SUSCEPTIBILITY ... View more
Last updated in GTR: 2019-07-01
Last annual review date for the lab: 2023-07-21 Past due LinkOut
At a Glance
Diagnosis
Breast-ovarian cancer, familial, susceptibility to, 1; Adrenocortical carcinoma, hereditary; Basal cell carcinoma, susceptibility to, 7 more...
Genes (7): Help
BRCA1 (17q21.31); BRCA2 (13q13.1); CDH1 (16q22.1); PALB2 (16p12.2); PTEN (10q23.31) more...
Molecular Genetics - Deletion/duplication analysis: Next-Generation (NGS)/Massively parallel sequencing (MPS); ...
Not provided
Not provided
Not provided
Ordering Information
Offered by: Help
Baylor Genetics
View lab's website
Test Order Code: Help
23000
Informed consent required: Help
Decline to answer
Pre-test genetic counseling required: Help
Decline to answer
Post-test genetic counseling required: Help
Decline to answer
Recommended fields not provided:
Conditions Help
Total conditions: 34
Condition/Phenotype Identifier
Test Targets
Genes Help
Total genes: 7
Gene Associated Condition Germline or Somatic Allele (Lab-provided) Variant in NCBI
Methodology
Total methods: 2
Method Category Help
Test method Help
Instrument *
Deletion/duplication analysis
Next-Generation (NGS)/Massively parallel sequencing (MPS)
Sequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
* Instrument: Not provided
Clinical Information
Test purpose: Help
Diagnosis
Recommended fields not provided:
Technical Information
Availability: Help
Tests performed
Entire test performed in-house
Analytical Validity: Help
The sequence (NGS) analytical validity for SNV is >99% sensitivity, >99% specificity, >99% accuracy. The deletion/duplication analytical validity for CNV is higher than 99.9% sensitivity, >99% specificity, >99% accuracy to detect one exon or greater deletions and two exon or greater insertion, LOD standard deviation over 0.12 or coverage < … View more
Proficiency testing (PT):
Is proficiency testing performed for this test? Help
No
Recommended fields not provided:
Regulatory Approval
FDA Review: Help
Not provided
Additional Information

IMPORTANT NOTE: NIH does not independently verify information submitted to GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.