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GTR Home > Conditions/Phenotypes > Mandibuloacral dysplasia progeroid syndrome

Mandibuloacral dysplasia progeroid syndrome

Summary

Mandibuloacral dysplasia progeroid syndrome (MDPS) is an autosomal recessive severe laminopathy-like disorder characterized by growth retardation, bone resorption, arterial calcification, renal glomerulosclerosis, and hypertension (Elouej et al., 2020). [from OMIM]

Genes See tests for all associated and related genes

  • Also known as: MDPS, metaxin-2, MTX2
    Summary: metaxin 2

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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