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GTR Home > Conditions/Phenotypes > Craniosynostosis 2

Craniosynostosis 2

Synonyms
Craniosynostosis Boston type; Craniosynostosis Warman type; MSX2-Related Craniosynostosis; Warman-Mulliken-Hayward syndrome
Modes of inheritance
Autosomal dominant inheritance (Orphanet)

Summary

Craniosynostosis is a primary abnormality of skull growth involving premature fusion of the cranial sutures such that the growth velocity of the skull often cannot match that of the developing brain. This produces skull deformity and, in some cases, raises intracranial pressure, which must be treated promptly to avoid permanent neurodevelopmental disability (summary by Fitzpatrick, 2013). For a discussion of genetic heterogeneity of craniosynostosis, see CRS1 (123100). [from OMIM]

Available tests

33 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Clinical tests (33 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CRS2, FPP, HOX8, MSH, PFM, PFM1, MSX2
    Summary: msh homeobox 2

Clinical features

Help
Imported from Human Phenotype Ontology (HPO)

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