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    SMIM10L2B small integral membrane protein 10 like 2B [ Homo sapiens (human) ]

    Gene ID: 644596, updated on 17-Sep-2024

    Summary

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    Official Symbol
    SMIM10L2Bprovided by HGNC
    Official Full Name
    small integral membrane protein 10 like 2Bprovided by HGNC
    Primary source
    HGNC:HGNC:34500
    See related
    Ensembl:ENSG00000196972 AllianceGenome:HGNC:34500
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LINC00086; LINC00087; SMIM10L2A; NCRNA00086; NCRNA00087
    Expression
    Broad expression in brain (RPKM 9.9), heart (RPKM 4.0) and 14 other tissues See more
    Orthologs
    all
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    Genomic context

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    See SMIM10L2B in Genome Data Viewer
    Location:
    Xq26.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (135094985..135098712, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (133420353..133424080, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (134229015..134232742, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chrX:134184927-134185713 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29979 Neighboring gene retrotransposon Gag like 8A Neighboring gene nucleolin pseudogene 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 21018 Neighboring gene Sharpr-MPRA regulatory region 8062 Neighboring gene SMIM10L2B antisense RNA 1 Neighboring gene embryonic testis differentiation homolog B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. The DNA sequence of the human X chromosome. Ross MT, et al. Nature, 2005 Mar 17. PMID 15772651, Free PMC Article
    2. VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Yue Y, et al. Cell Discov, 2018. PMID 29507755, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • FLJ41308, RP11-85L21.2

    General protein information

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    Preferred Names
    small integral membrane protein 10-like protein 2B
    Names
    Small integral membrane protein 10-like protein 2A
    long intergenic non-protein coding RNA 87

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348255.2 → NP_001335184.1  small integral membrane protein 10-like protein 2B

      Status: VALIDATED

      Source sequence(s)
      AL590325
      Consensus CDS
      CCDS87780.1
      UniProtKB/Swiss-Prot
      P0DMW4, P0DMW5
      Related
      ENSP00000487709.1, ENST00000433425.4
      Conserved Domains (1) summary
      pfam15118
      Location:21 → 77
      DUF4560; Domain of unknown function (DUF4560)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      135094985..135098712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      133420353..133424080 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0DMW5.1 GenPept UniProtKB/Swiss-Prot:P0DMW5

    Gene LinkOut

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