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Conserved domains on  [gi|1134612278|ref|NP_001335184|]
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small integral membrane protein 10-like protein 2B [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4560 super family cl20987
Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. ...
 21-77 3.37e-25

Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 66 and 78 amino acids in length. There are two conserved sequence motifs: FCK and RTL.


The actual alignment was detected with superfamily member pfam15118:

Pssm-ID: 434473  Cd Length: 64  Bit Score: 88.36  E-value: 3.37e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1134612278 21 VRLSRSAAARgSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRI 77
Cdd:pfam15118  9 LRASGSAGAR-SYGVFCKGLTRTLLIFFDLAWRLRMNFPYFYIVASVILNVRLQVHI 64
 
Name Accession Description Interval E-value
DUF4560 pfam15118
Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. ...
 21-77 3.37e-25

Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 66 and 78 amino acids in length. There are two conserved sequence motifs: FCK and RTL.


Pssm-ID: 434473  Cd Length: 64  Bit Score: 88.36  E-value: 3.37e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1134612278 21 VRLSRSAAARgSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRI 77
Cdd:pfam15118  9 LRASGSAGAR-SYGVFCKGLTRTLLIFFDLAWRLRMNFPYFYIVASVILNVRLQVHI 64
 
Name Accession Description Interval E-value
DUF4560 pfam15118
Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. ...
 21-77 3.37e-25

Domain of unknown function (DUF4560); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 66 and 78 amino acids in length. There are two conserved sequence motifs: FCK and RTL.


Pssm-ID: 434473  Cd Length: 64  Bit Score: 88.36  E-value: 3.37e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 1134612278 21 VRLSRSAAARgSYGAFCKGLTRTLLTFFDLAWRLRMNFPYFYIVASVMLNVRLQVRI 77
Cdd:pfam15118  9 LRASGSAGAR-SYGVFCKGLTRTLLIFFDLAWRLRMNFPYFYIVASVILNVRLQVHI 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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