Pcdhb16 protocadherin beta 16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Pcdhb16provided by MGI
Official Full Name: protocadherin beta 16provided by MGI
Primary source: MGI:MGI:2136752
See related: Ensembl:ENSMUSG00000047910 AllianceGenome:MGI:2136752
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Pcdhb8; PcdhbP
Summary: Predicted to be involved in cell adhesion. Located in photoreceptor connecting cilium; photoreceptor disc membrane; and postsynaptic membrane. Is expressed in several structures, including central nervous system and retina. Orthologous to human PCDHB13 (protocadherin beta 13) and PCDHB8 (protocadherin beta 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: 18 B3; 18 19.5 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	18	NC_000084.7 (37610821..37616091)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	18	NC_000084.6 (37477768..37483038)

Chromosome 18 - NC_000084.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1) 1 citation

General gene information

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Markers

Pcdhb16 (e-PCR), detects polymorphism
- UniSTS:515916

Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in cell adhesion	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in photoreceptor connecting cilium	IDA Inferred from Direct Assay more info	PubMed
located_in photoreceptor disc membrane	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in postsynaptic membrane	IDA Inferred from Direct Assay more info	PubMed
located_in synapse	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: protocadherin beta 16

Names: Protocadherin-betaP; cell-cell adhesion molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053141.3 → NP_444371.3 protocadherin beta 16 precursor

See identical proteins and their annotated locations for NP_444371.3

Status: VALIDATED

Source sequence(s)

AK036829, BC116625, BP762533, CJ182908

Consensus CDS

CCDS29182.1

UniProtKB/TrEMBL

Q14BM8, Q8CB45, Q91Y03

Related

ENSMUSP00000056347.6, ENSMUST00000051442.7

Conserved Domains (3) summary

cd11304
Location:248 → 344

Cadherin_repeat; Cadherin tandem repeat domain

pfam08266
Location:32 → 113

Cadherin_2; Cadherin-like

pfam16492
Location:687 → 770

Cadherin_C_2; Cadherin cytoplasmic C-terminal