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Series GSE98564 Query DataSets for GSE98564
Status Public on Apr 10, 2018
Title Gene expression biomarkers for neurobehavioral impairment from total sleep deprivation microarray data [D6]
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Healthy human adults were recruited to a sleep lab at Washington State University and remained there 7 consecutive days. Six received a well-rested Control condition of 10 h Time-In-Bed (TIB) nightly.
Another 11 subjects underwent Sleep Deprivation. They had a Baseline with 10 h TIB, followed by an Experimental phase of 62 h continued wakefulness, and finally two nights of 10 h TIB before dismissal. Blood draws on one Baseline day, one Experimental day, and one Recovery day were used for gene expression microarrays.
 
Overall design Blood gene expression microarray data was compared between well-rested Control human subjects and a Sleep Deprived subject group. Furthermore the expression data was related to attention lapses as measured by the Psychomotor Vigilance Test. Three of the Sleep Deprivation subjects were characterized as fatigue resistant based on their PVT lapse profile; resistance was not determined for Control subjects.
 
Contributor(s) Uyhelji HA, Kupfer DK, White VL, Burian DM
Citation(s) 29739334
Submission date May 04, 2017
Last update date Jul 25, 2021
Contact name Hilary A Uyhelji
Organization name Federal Aviation Administration
Department Civil Aerospace Medical Institute
Street address 6500 S. MacArthur Blvd.
City Oklahoma City
State/province OK
ZIP/Postal code 73169
Country USA
 
Platforms (1)
GPL6244 [HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version]
Samples (199)
GSM2599763 Control subject 6045 blood collection 01 [D6]
GSM2599764 Control subject 6045 blood collection 02 [D6]
GSM2599765 Control subject 6045 blood collection 03 [D6]
This SubSeries is part of SuperSeries:
GSE98582 Exploring gene expression biomarker candidates for neurobehavioral impairment from total sleep deprivation
Relations
BioProject PRJNA385579

Download family Format
SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE98564_RAW.tar 708.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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