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Series GSE75091 Query DataSets for GSE75091
Status Public on Jun 15, 2016
Title Genome-wide analysis of uterine natural killer cell gene expression from lean and obese women in early pregnancy
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Analysis of gene expression in uterine natural killer (NK) cells purified from either lean (control) or obese pregnanct women. The studys' aim is to identify differentially expressed genes and pathways in natural killer cells that are affected by maternal obesity. Results provide mechanitic insight into gene pathways altered in the condition of obeisty.
Overall design Total RNA obtained from immuno-magnetic bead purified natural killer cells from uterine decidual mucosa from 7 to 10 week old pregnancies from 13 lean (BMI 20-24.9) and 11 obese (BMI >30) women. All women were between 19 and 35 years of age. In addition to BMI, blood serum CRP (hsCRP), a measure of inflammation, was measured via ELISA.
Citation(s) 27699222
Submission date Nov 17, 2015
Last update date Jun 27, 2019
Contact name Alexander G Beristain
Phone 604-875-3573
Organization name The University of British Columbia
Department Obstetrics & Gynecology
Lab Beristain lab
Street address 950 West 28th Ave
City Vancouver
State/province BC
ZIP/Postal code V5Z 4H4
Country Canada
Platforms (1)
GPL10558 Illumina HumanHT-12 V4.0 expression beadchip
Samples (24)
GSM1942490 D181_Obese
GSM1942491 D182_Control
GSM1942492 D68_Obese
BioProject PRJNA302438

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE75091_RAW.tar 26.2 Mb (http)(custom) TAR
GSE75091_non-normalized.txt.gz 9.8 Mb (ftp)(http) TXT
Processed data included within Sample table

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