|
Status |
Public on Jun 22, 2008 |
Title |
NY218 |
Sample type |
genomic |
|
|
Source name |
hepatocellular carcinoma
|
Organism |
Homo sapiens |
Characteristics |
BCLC_staging : C Age : 52 Sex : F Code+F1 : resection Class : Inflammation AFP : 413.9 TP53 mutation : 0 CTNNB1 mutation : 0 Immunocytochemistry : pRPS6 : 0 Immunocytochemistry : pIGFR1 : 0 Immunocytochemistry : pAkt : 0 Immunocytochemistry : CTNNB1 : 1
|
Growth protocol |
Tumors obtained at time of surgical resection or transplantation, according to institutional review board approved protocols
|
Extracted molecule |
genomic DNA |
Extraction protocol |
Genomic DNA was extracted with the ChargeSwitch gDNA mini kit (Invitrogen) according to manufacturer's instructions, followed by phenol-chloroform extraction
|
Label |
biotin
|
Label protocol |
Affymetrix standard procedure
|
|
|
Hybridization protocol |
Affymetrix standard procedure
|
Scan protocol |
Affymetrix standard procedure
|
Description |
103 hepatocellular carcinomas and 95 adjacent cirrhotic, non-tumoral liver tissue were obtained at the time of surgical resection of orthotopic transplantation.
|
Data processing |
Copy numbers were estimated by the GenePattern SNPFileCreator module
|
|
|
Submission date |
Dec 11, 2007 |
Last update date |
Aug 14, 2011 |
Contact name |
Derek Chiang |
E-mail(s) |
chiang@med.unc.edu
|
Organization name |
University of North Carolina
|
Department |
Department of Genetics
|
Street address |
UNC Lineberger Cancer Center, 450 West Drive, CB #7295
|
City |
Chapel Hill |
State/province |
NC |
ZIP/Postal code |
27599-7295 |
Country |
USA |
|
|
Platform ID |
GPL3720 |
Series (2) |
GSE9829 |
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma |
GSE9845 |
Copy number alterations of 103 hepatocellular carcinomas with hepatitis C virus etiology |
|