|
| Status |
Public on Dec 19, 2018 |
| Title |
A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients [RNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The Illumina NextSeq500 was used to sequence the gene expression profiles of 21 ileal fibroblast samples. Samples included 6 control samples and 15 Crohn’s disease samples. The Crohn’s disease samples can be further subdivided into inflamed (4), non-inflamed (6) and stenotic (5) samples.
This experiment together was performed in conjunction with a DNA methylation experiment (GSE99788). Use Supplemental Table 2 of the manuscript to quickly find the samples that were present in both experiments.
|
| |
|
| Overall design |
RNA from 21 samples were sequenced on the Illumina NextSeq500
|
| |
|
| Contributor(s) |
Li Yim AY, de Bruyn JR, Duijvis NW, Sharp C, Ferrero E, de Jonge WJ, Wildenberg ME, Mannens MM, Buskens CJ, D’Haens GR, Henneman P, te Velde AA |
| Citation(s) |
30589872 |
| |
| Submission date |
Jun 08, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Peter Henneman |
| Organization name |
Academic Medical Center Amsterdam
|
| Department |
Clinical Genetics
|
| Lab |
Genome Diagnostics
|
| Street address |
Meibergdreef 9
|
| City |
Amsterdam |
| State/province |
Noord Holland |
| ZIP/Postal code |
1105 AZ |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (21)
|
| GSM2653405 |
Fibroblast Non_CD sample 28 from patient 15 |
| GSM2653406 |
Fibroblast Non_CD sample 29 from patient 15 |
| GSM2653407 |
Fibroblast Non_CD sample 30 from patient 15 |
| GSM2653408 |
Fibroblast Non_CD sample 4 from patient 3 |
| GSM2653409 |
Fibroblast Non_CD sample 7 from patient 5 |
| GSM2653410 |
Fibroblast Non_CD sample 18 from patient 10 |
| GSM2653411 |
Fibroblast NINF sample 19 from patient 11 |
| GSM2653412 |
Fibroblast NINF sample 2 from patient 2 |
| GSM2653413 |
Fibroblast NINF sample 16 from patient 9 |
| GSM2653414 |
Fibroblast NINF sample 1 from patient 1 |
| GSM2653415 |
Fibroblast NINF sample 9 from patient 7 |
| GSM2653416 |
Fibroblast NINF sample 14 from patient 8 |
| GSM2653417 |
Fibroblast INF sample 15 from patient 8 |
| GSM2653418 |
Fibroblast INF sample 11 from patient 7 |
| GSM2653419 |
Fibroblast INF sample 8 from patient 6 |
| GSM2653420 |
Fibroblast INF sample 20 from patient 11 |
| GSM2653421 |
Fibroblast STEN sample 24 from patient 12 |
| GSM2653422 |
Fibroblast STEN sample 26 from patient 14 |
| GSM2653423 |
Fibroblast STEN sample 27 from patient 14 |
| GSM2653424 |
Fibroblast STEN sample 25 from patient 13 |
| GSM2653425 |
Fibroblast STEN sample 12 from patient 7 |
|
| Relations |
| BioProject |
PRJNA389715 |
| SRA |
SRP108847 |
Less...
More...