|
| Status |
Public on Jun 06, 2017 |
| Title |
Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using RNAseq we describe transcriptional changes downstream of liver-specific knockout of RNaseH1, including effects on mitochondrial function, fibrosis and cell cycle
|
| |
|
| Overall design |
We perform RNAseq on mouse livers under conditions of constitutive or inducible knockout of RNaseH1
|
| |
|
| Contributor(s) |
Lima W |
| Citation(s) |
27131367 |
| |
| Submission date |
Jun 05, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Sagar S Damle |
| E-mail(s) |
sdamle@ionisph.com
|
| Organization name |
Ionis Pharmaceuticals
|
| Street address |
2855 Gazelle Ct
|
| City |
Carlsbad |
| State/province |
CA |
| ZIP/Postal code |
92010 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (23)
|
|
| Relations |
| BioProject |
PRJNA389251 |
| SRA |
SRP108593 |
Less...
More...