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| Status |
Public on Aug 01, 2019 |
| Title |
H3K36me3 protects the mouse epigenome from single nucleotide variations [mRNA-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goals of this project are to study the transcriptome profiling (RNA-seq) of mouse embryonic stem cells by histone mutants incorporation (H3.1K3M, H3.1K36M vs H3.1wt) or shRNA-mediated knockdown of methyl-transferase Suv39h1/h2 (shSuv39h1, shSuv39h2 vs shNC)
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| Overall design |
mRNA profiles of mES stable cell lines with overexpression of H3.1WT, H3.1K9M, H3.1K36M and shNC, shSuv39h1, shSuv39h2 were generated by deep sequencing, in double, using Illumina next-generation sequencing.
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| Contributor(s) |
Sun F, Kang X, Chang J |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 22, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Jin Sun |
| E-mail(s) |
sunjin@tongji.edu.cn
|
| Organization name |
Tongji University
|
| Department |
life science and technology
|
| Lab |
Jiang
|
| Street address |
siping1239
|
| City |
shanghai |
| ZIP/Postal code |
200092 |
| Country |
China |
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| Platforms (1) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE99156 |
H3K36me3 protects the mouse epigenome from single nucleotide variations |
|
| Relations |
| BioProject |
PRJNA387443 |
| SRA |
SRP107768 |
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