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| Status |
Public on May 22, 2017 |
| Title |
SNP genotype data from induced Pluripotent Stem cells from healthy control donors |
| Organism |
Homo sapiens |
| Experiment type |
SNP genotyping by SNP array
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| Summary |
We have generated human induced Pluripotent Stem cells (hiPSc) using Retroviral or Sendai virus-mediated delivery of reprogramming factors. hiPSc lines have been screened using SNP array to assess chromosomal stability (alongside the fibroblast lines from which they derived), and validation of the pluripotency of the hiPSc lines is provided by Pluritest assessment of transcriptome datasets, prior to differentiation and downstream assays.
MAPT genetic variation and neuronal maturity alter isoform expression affecting axonal transport in iPSC-derived dopamine neurons. Joel E Beevers, Mang-Ching Lai, Heather A Booth, Federico Zambon, Laura Parkkinen, Jane Vowles, Sally A Cowley, Richard Wade-Martins, Tara M Caffrey. Stem Cell Reports 2017
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| Overall design |
human iPSc lines were derived from human dermal fibroblasts from 3 control donors (newly-derived lines are reported here; for lines that have been previously described and for fibroblasts from which lines have been derived, refer to current manuscript for relevant references). SNP and gene expression datasets were generated.
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| Contributor(s) |
Beevers JE, Lai M, Booth HA, Zambon F, Parkkinen L, Vowles J, Cowley SA, Wade-Martins R, Caffrey TM |
| Citation missing |
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| Submission date |
May 21, 2017 |
| Last update date |
Jan 24, 2018 |
| Contact name |
Sally A Cowley |
| E-mail(s) |
sally.cowley@path.ox.ac.uk
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| Phone |
+44 (0) 1865 275600
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| Organization name |
University of Oxford
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| Department |
Sir William Dunn School of Pathology
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| Lab |
James Martin Stem Cell Facility
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| Street address |
South Parks Road
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| City |
Oxford |
| ZIP/Postal code |
OX1 3RE |
| Country |
United Kingdom |
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| Platforms (2) |
| GPL13829 |
Illumina HumanCytoSNP-12 v2.1 BeadChip |
| GPL21168 |
HumanOmniExpress-24 v1.0 BeadChip [SNP_ID version] |
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| Samples (3) |
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| This SubSeries is part of SuperSeries: |
| GSE99125 |
Gene Expression and SNP genotype data from induced Pluripotent Stem cells from healthy control donors |
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| Relations |
| BioProject |
PRJNA387381 |
