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| Status |
Public on Apr 25, 2017 |
| Title |
Differential gene expression pattern of mouse livers transfected with dual oncogenes (day-3 post-injection data set) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To understand global gene expression patterns of mouse livers upon dual-oncogene transfection, RNA sequencing and analysis were conducted on liver samples from Shp2F/F or Shp2∆H (Shp2F/F:Alb-cre) mice hydrodynamically injected with the combination of Met/β-Catenin or Met/PIK3CA .
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| Overall design |
18 mice from 6 experimental groups (n=3 for each group) were included in the experiment. Group1: Age-matched untreated Shp2F/F control mice; Group2: Age-matched Shp2ΔH mice; Group3: Met/β-Catenin hydrodynamically injected Shp2F/F mice; Group4: Met/β-Catenin hydrodynamically injected Shp2ΔH mice; Group5: Met/PIK3CA hydrodynamically injected Shp2F/F mice; Group6: Met/PIK3CA hydrodynamically injected Shp2ΔH mice. Total RNA was extracted on day3 post-injection from liver of each mouse.
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| Contributor(s) |
Li Y, Liu J, Feng G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Apr 19, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Jijun Liu |
| E-mail(s) |
jil655@ucsd.edu
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| Phone |
8586990922
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| Organization name |
UC San Diego
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| Department |
Pathology
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| Lab |
Dr. Gen-Sheng Feng Lab
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| Street address |
Rm1220 Bay-C, Biomedical Research Facility II, 9500 Gilman Drive
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| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92093 |
| Country |
USA |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (18)
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| Relations |
| BioProject |
PRJNA383590 |
| SRA |
SRP104319 |
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