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| Status |
Public on Aug 17, 2017 |
| Title |
Striatal transcriptome analysis of Shank3-overexpressing mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Shank3 is a core excitatory postsynaptic protein enriched in the striatum. We have previously generated and characterized Shank3-overexpressing transgenic mice, and found that these mice exhibited manic-like behavioral phenotypes. To understand molecular mechanisms underlying the behavioral changes, we performed transcriptome (RNA-sequencing) analysis of the striatal tissues from 12-week-old wild-type and Shank3 transgenic mice.
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| Overall design |
Striatal transcriptome of 12-week-old wild-type and Shank3 transgenic (TG) mice.
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| Contributor(s) |
Han K, Lee Y, Kang H |
| Citation(s) |
28701918 |
| |
| Submission date |
Apr 09, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Kihoon Han |
| E-mail(s) |
neurohan@korea.ac.kr
|
| Organization name |
Korea University College of Medicine
|
| Department |
Neuroscience
|
| Street address |
73, Inchon-ro, Seongbuk-gu
|
| City |
Seoul |
| ZIP/Postal code |
02841 |
| Country |
South Korea |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA382260 |
| SRA |
SRP103754 |
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