|
| Status |
Public on Jan 03, 2018 |
| Title |
Stabilization of NIK suppresses MLL-AF9-induced acute myeloid leukemia |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Comparison of transcriptome between control and NIK-stabilized leukemia stem cells
|
| |
|
| Overall design |
murine MLL-AF9 acute myeloid leukemia was generated using bone marrow progenitor cells (lin-cKit+) from NIKERT2 mice (crossing Rosa-loxp-STOP-loxp-NIK mice with Rosa-CreERT2 mice). Leukemia stem cells were sorted by FACS from tamoxifen treated (LSPCT group) and untreated (LSPC group) fully developed leukemia mice and used for RNAseq analysis.
|
| |
|
| Contributor(s) |
Zhao C |
| Citation(s) |
29320732 |
| |
| Submission date |
Apr 04, 2017 |
| Last update date |
Jul 31, 2019 |
| Contact name |
Thomas B Bair |
| E-mail(s) |
iihg-bioinformatics@uiowa.edu
|
| Organization name |
University of Iowa
|
| Street address |
335 EMRB
|
| City |
Iowa City |
| State/province |
IA |
| ZIP/Postal code |
52242 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA381614 |
| SRA |
SRP103019 |
Less...
More...