|
| Status |
Public on Apr 27, 2017 |
| Title |
Ebf2 Knockout Brown Adipose Tissue [RNA-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The helix-loop-helix transcription factor Early B-Cell Factor 2 (EBF2) is required for the differentiation and function of brown and beige adipocytes. The presumptive BAT in Ebf2 knockout (KO) animals has a white-fat like morphology and molecular profile. We examined the transcriptome of WT and Ebf2 KO BAT by high-throughput sequencing.
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| |
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| Overall design |
Two control replicates (wildtype mice) and two experimental replicates (Ebf2 KO mice) were analyzed
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| |
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| Contributor(s) |
Shapira SN, Lim H, Sakers AP, Ishibashi J, Harms MJ, Rajakumari S, Won K, Seale P |
| Citation(s) |
28428261 |
| |
| Submission date |
Mar 28, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Hee-Woong Lim |
| Organization name |
Cincinnati Children's Hospital Medical Center
|
| Department |
Division of Biomedical Informatics
|
| Street address |
3333 Burnet Ave. MLC 7024
|
| City |
Cincinnati |
| State/province |
Ohio |
| ZIP/Postal code |
45229 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (4)
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| This SubSeries is part of SuperSeries: |
| GSE97116 |
Ebf2 Knockout Brown Adipose Tissue |
|
| Relations |
| BioProject |
PRJNA380851 |
| SRA |
SRP102659 |
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