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| Status |
Public on Jul 07, 2017 |
| Title |
Cell type-specific alternative splicing during mammalian neuronal differentiation |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Alternative precursor-mRNA splicing (AS) is a key regulation of gene expression and protein diversity. AS is highly happened in the nervous system and misregulation of AS caused neurological diseases. In current research, we identified and validated the differential AS events from purified neural progenitor cells (NPCs) and neurons. Our data demonstrated a systematic characterization of AS events between endogenous NPCs and neurons, which may serve as a useful resource for further investigations.
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| |
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| Overall design |
Differential alternative splicings of neural progenitor cells (NPCs) and neurons were analyzed
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| |
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| Contributor(s) |
Liu J, Wu X, Lu Q |
| Citation(s) |
28651367 |
| |
| Submission date |
Mar 23, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Xiwei Wu |
| E-mail(s) |
xwu@coh.org
|
| Organization name |
City of Hope National Medical Center
|
| Department |
Computational and Quantitative Medicine
|
| Street address |
1500 E. Duarte Rd.
|
| City |
Duarte |
| State/province |
CA |
| ZIP/Postal code |
91010 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA380202 |
| SRA |
SRP102347 |
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