|
| Status |
Public on May 10, 2017 |
| Title |
RNA Sequencing of Pinometostat Sensitive and Resistant Paired Cell Lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
MLL-r cell lines KOPN-8 and NOMO-1 were cultured with pinometostat to derive treatment emergent resistant pools. RNA sequencing was performed on the resistant pools to generate hypotheses around mechanisms of resistance
|
| |
|
| Overall design |
RNA-sequencing of KOPN-8 and NOMO-1 cell lines treated long term (ie resistant) and short term (sensitive) with pinometostat, along with DMSO matched controls
|
| |
|
| Contributor(s) |
Campbell CT, Daigle SR |
| Citation(s) |
28428443 |
| |
| Submission date |
Feb 13, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Carly T Campbell |
| E-mail(s) |
ccampbell@epizyme.com
|
| Organization name |
Epizyme
|
| Street address |
400 Technology Sq, 4th Fl
|
| City |
Cambridge |
| State/province |
Massachusetts |
| ZIP/Postal code |
02139 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (24)
|
|
| Relations |
| BioProject |
PRJNA374582 |
| SRA |
SRP099457 |
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