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Series GSE94159 Query DataSets for GSE94159
Status Public on Jul 09, 2018
Title Gene expression changes after blockade of Frizzled7 in murine intestinal organoids
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary RNA was isolated from intestinal primary mouse organoids at 6h and 24h after treatment with dFz7-21 peptide, Fz7-21S (mock) peptide and DMSO.
These two time points were specifically selected to investigate early and late transcriptional responses after Fzd7 inhibition.
The "SAMPLE_ID" sample characteristic is a sample identifier internal to Genentech.
The ID of this project in Genentech's ExpressionPlot database is PRJ0010717
 
Overall design Gene expression profiling of intestinal primary mouse organoids treated with dFz7-21 - a small molecule peptide that specifically and potently blocks Frizzled 7
 
Contributor(s) Piskol R, de Sousa e Melo F, Nile A
Citation(s) 29632413
Submission date Jan 27, 2017
Last update date May 15, 2019
Contact name Robert Piskol
E-mail(s) piskolr@gene.com
Organization name Genentech Inc.
Department Bioinformatics
Street address 1 DNA Way
City South San Francisco
State/province CA
ZIP/Postal code 94080
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (24)
GSM2471204 SAM24326098 Intestine Small SAM24326098 Fz7-21S_24h_1 24h Fz7-21S
GSM2471205 SAM24326080 Intestine Small SAM24326080 DMSO 6h_3 6h DMSO
GSM2471206 SAM24326097 Intestine Small SAM24326097 dFz7-21_24h_4 24h dFz7-21
Relations
BioProject PRJNA369100
SRA SRP098128

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE94159_RAW.tar 7.0 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
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