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| Status |
Public on Jan 27, 2017 |
| Title |
Subepithelial telocytes are an indispensable source of Wnt ligands supporting intestinal crypts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We successfully sequenced and annotated Foxl1 positive and Foxl1 negative mouse intestine mesenchymal cells ( triplicate for each group). We also report that Foxl1 positive cells express molecules of key signaling pathways such as Wnt, BMP,Shh, Tgfb and NFkB.
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| Overall design |
Foxl1 positive and Foxl1 negative sorted mouse intestine mesenchymal cells from three Foxl1Cre;Rosa-YFP or Foxl1Cre;Rosa-mTmG mice were sequenced.
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| Contributor(s) |
Shoshkes-Carmel M, Wangensteen KJ, Wang YJ, Toth B, Itzkovitz S, Kondo A, Massasa EE, Kaestner KH |
| Citation(s) |
29720649 |
| |
| Submission date |
Jan 25, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Michal Shoshkes-Carmel |
| E-mail(s) |
michalsh@mail.med.upenn.edu
|
| Organization name |
University of Pennsylvania
|
| Department |
Genetics
|
| Lab |
Klaus Kaestner
|
| Street address |
3400 Civic Center Blvd, 12-161
|
| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA368802 |
| SRA |
SRP097846 |
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