|
| Status |
Public on May 17, 2018 |
| Title |
TOX expression governs the encephalitogenic potential of microbe-induced autoreactive CD8+ T cells by reducing immune checkpoint sensitivity |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We report that TOX represses a terminal differentiation signature in CD8+ T cells by repressing Id-2 expression
|
| |
|
| Overall design |
Examination of TOX-specific peaks in OT-1 genome
|
| |
|
| Contributor(s) |
Merkler D, Page N |
| Citation(s) |
29768177 |
| |
| Submission date |
Jan 23, 2017 |
| Last update date |
May 15, 2019 |
| Contact name |
Sylvain LEMEILLE |
| Organization name |
University of Geneva Medical School
|
| Department |
Department of Pathology and Immunology
|
| Street address |
1 rue Michel-Servet
|
| City |
Geneva |
| ZIP/Postal code |
1211 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (3) |
|
| Relations |
| BioProject |
PRJNA362888 |
| SRA |
SRP097627 |
