|
| Status |
Public on Jan 20, 2017 |
| Title |
MLL2, but not MLL1, plays a major role to sustain leukemia survival [RNA-seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We investigated the effect of Mll1, Mll2 and Mll1;Mll2 deletion on gene expression in MLL-AF9-transformed cells.
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| |
|
| Overall design |
MLL-AF9 cells transformed from c-Kit-enriched BM cells were treated with ethanol or 100nM 4-OHT for 24 hours. After removing the drug, cells were continued to culture for 2 days and then collected for RNA extraction and RNA-seq.
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| |
|
| Contributor(s) |
Chen Y, Ernst P, Jones K |
| Citation(s) |
28609655 |
| |
| Submission date |
Jan 13, 2017 |
| Last update date |
Jun 05, 2019 |
| Contact name |
Kenneth L Jones |
| Organization name |
Bioinformatic Solutions LLC
|
| Street address |
1309 Coffeen Avenue STE 10090
|
| City |
Sheridan |
| State/province |
Wyoming |
| ZIP/Postal code |
82801 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
|
| Samples (12)
|
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| This SubSeries is part of SuperSeries: |
| GSE93623 |
MLL2, but not MLL1, plays a major role to sustain leukemia survival |
|
| Relations |
| BioProject |
PRJNA362637 |
| SRA |
SRP097222 |
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