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| Status |
Public on Feb 28, 2017 |
| Title |
Pentraxin-3 is a PI 3-Kinase Effector that Regulates Stem-Cell-Like Traits in Basal-Like Breast Cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
MCF10A cells: control vs. PIK3CA mutant (H1047R)
Transcriptional profiling of MCF10A comparing control (expressing JP1520-PIK3CA-WT; Addgen plasmid #14570) and PIK3CA mutant (JP1520-PIK3CA-H1047R; Addgene plasmic#14572). Goal was to determine the effects of the PIK3CA H1047R mutation in the on global gene expression in MCF10A cells.
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| |
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| Overall design |
Two-condition experiment, ES vs. TF-ES cells. Biological replicates: 4 control replicates, 3 transfected replicates.
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| |
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| Contributor(s) |
Henry W, Toker A, Karnoub A |
| Citation(s) |
28223411 |
| |
| Submission date |
Jan 11, 2017 |
| Last update date |
Apr 23, 2018 |
| Contact name |
Antoine Elias Karnoub |
| E-mail(s) |
akarnoub@bidmc.harvard.edu
|
| Phone |
617-735-2082
|
| Organization name |
Beth Israel Deaconess Medical Center and Harvard Medical School
|
| Department |
Pathology
|
| Lab |
Karnoub Lab
|
| Street address |
3 Blackfan Circle
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL16699 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA360951 |
