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Series GSE92721 Query DataSets for GSE92721
Status Public on Apr 18, 2017
Title Transdifferentiation as a mechanism of treatment resistance in a mouse model of castration-resistant prostate cancer
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Analysis of transcriptome of prostate tissue from the anterior lobe or tumor from 9, 12, 13, 14, and 16 months old mouse
Prostate tissue or tumor from 9 month old Nkx3.1CreERT2/+ mice, 14 month old Nkx3.1CreERT2/+;Ptenflox/flox mice (intact, treated with vehicle), 16 month old Nkx3.1CreERT2/+;Ptenflox/flox mice (castrated, treated with vehicle or abiraterone), 12 month old Nkx3.1CreERT2/+;Ptenflox/flox;P53flox/flox mice(intact, treated with vehicle), 13 month old Nkx3.1CreERT2/+;Ptenflox/flox;P53flox/flox mice (castrated, treated with vehicle or abiraterone) was harvested, and snap frozen for subsequent molecular analysis
 
Overall design Total RNA obtained from prostate tissues or tumors. Prostate tissues or tumors were harvested and processed for RNA isolation and transcriptome analysis using the MagMAX RNA isolation kit (Ambion).
 
Contributor(s) Zou M, Mitrofanova A, Floch N, Abate-Shen C
Citation(s) 28411207
Submission date Dec 21, 2016
Last update date May 15, 2019
Contact name Antonina Mitrofanova
E-mail(s) mitrofanova.antonina@hotmail.com
Organization name Rutgers University
Street address 65 Bergen Street, Rm 923B
City Newark
State/province NJ
ZIP/Postal code 07107
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (29)
GSM2436423 NF005_N prostate tissue
GSM2436424 NF007_N prostate tissue
GSM2436425 NF008_N prostate tissue
Relations
BioProject PRJNA358422
SRA SRP095488

Download family Format
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE92721_RNAseq_normalized.txt.gz 3.6 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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