|
| Status |
Public on Dec 20, 2016 |
| Title |
Aberrant connective tissue differentiation towards cartilage and bone underlies human keloids in African Americans |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Pilot study: Observational clinical study
|
| |
|
| Overall design |
To characterize keloids in African Americans, we performed transcriptional profiling of biopsies from large chronic keloids, adjacent nonlesional (NL) skin (n=3) and a newly formed keloid lesion using Affymetrix HGU133 2.0 plus arrays. Quantitative RT-PCR (qRT-PCR) and immunohistochemistry staining were done to confirm increased expression of relevant genes
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| |
|
| Contributor(s) |
Fuentes-Duculan J, Suárez-Fariñas M, Garcet S, Tirgan MH, Krueger JG |
| Citation(s) |
27943413 |
| |
| Submission date |
Dec 19, 2016 |
| Last update date |
Mar 25, 2019 |
| Contact name |
Mayte Suarez-Farinas |
| E-mail(s) |
mayte.suarezfarinas@mssm.edu
|
| Organization name |
Mount SinaiSchool of Medicine
|
| Street address |
1425 Madison Ave, L2-70C, Box 1077,
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10075 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (7)
|
|
| Relations |
| BioProject |
PRJNA358057 |
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