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| Status |
Public on Nov 15, 2017 |
| Title |
Circulating microRNAs: a novel potential biomarker for diagnosing acute aortic dissection |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
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| Summary |
Microarrays with 1,205 human microRNAs and 142 viral microRNAs were used for screening candidate diagnostic markers in the 3 categories of subjects from 24 plasma samples including acute aortic dissection, healthy and aortic aneurysm subjects. There were two microRNAs overlapping in the 3 group comparisons. Finally, 16 candidate microRNAs discovered via microarrays were selected for the further validation.
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| Overall design |
A microarray containing probes for 1,205 human microRNAs and 142 viral microRNAs was initially used to screen the significant differential expression levels of microRNAs between the acute aortic dissection (n=8) and control groups (n=16, 8 aortic aneurysm patients and 8 healthy volunteers).
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| |
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| Contributor(s) |
Dong J, Zhou J, Jing Z |
| Citation(s) |
28986538 |
| |
| Submission date |
Dec 15, 2016 |
| Last update date |
Nov 15, 2017 |
| Contact name |
Jian Dong |
| E-mail(s) |
dr_dongj@163.com
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| Phone |
+86-18801790869
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| Organization name |
Changhai Hospital
|
| Department |
Department of Vascular Surgery
|
| Street address |
168 Changhai Rd
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| City |
Shanghai |
| ZIP/Postal code |
200433 |
| Country |
China |
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| Platforms (1) |
| GPL16770 |
Agilent-031181 Unrestricted_Human_miRNA_V16.0_Microarray (miRBase release 16.0 miRNA ID version) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA357550 |
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