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| Status |
Public on Aug 28, 2018 |
| Title |
RNA-seq of TPR50 Tau P301S Transgenic Mouse in different brain regions and time-points |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Purpose: The goal of this study was to assess gene expression changes in TPR50 Tau transgenic mice. The mice was backcrossed with 2 divergent mouse strains - DBA and FVB along with the parent C57BL6 strain. The resulting F1 hybrids were used for further analysis.
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| |
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| Overall design |
Brain samples from F1 hybrids were isolated and falsh frozen. RNA was isolated using miRNeasy kit and RNA-seq was performed using unstranded Illumina poly-A library prep kit.
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| Contributor(s) |
Swarup V, Geschwind DH |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Nov 30, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Vivek Swarup |
| E-mail(s) |
vswarup@uci.edu
|
| Organization name |
University of California Irvine
|
| Department |
Neurobiology and Behavior
|
| Street address |
3400 Bio Sci 3
|
| City |
Irvine |
| State/province |
CALIFORNIA |
| ZIP/Postal code |
92697 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (277)
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| This SubSeries is part of SuperSeries: |
| GSE90696 |
Identification of evolutionary conserved gene networks that mediate neurodegenerative dementia |
|
| Relations |
| BioProject |
PRJNA355398 |
| SRA |
SRP094108 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE90693_RAW.tar |
34.5 Mb |
(http)(custom) |
TAR (of TXT) |
| GSE90693_RawCountsData_TPR50_3months_AllRegions.txt.gz |
3.9 Mb |
(ftp)(http) |
TXT |
| GSE90693_RawCountsData_TPR50_6months_AllRegions.txt.gz |
3.8 Mb |
(ftp)(http) |
TXT |
| GSE90693_metaData_SampleSheet_TPR50_mRNAseq.txt.gz |
1.9 Kb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_BrainStem_3months.txt.gz |
2.4 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_BrainStem_6months.txt.gz |
1.7 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Cerebellum_3months.txt.gz |
2.5 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Cerebellum_6months.txt.gz |
1.7 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Cortex_3months.txt.gz |
2.5 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Cortex_6months.txt.gz |
1.8 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Hippocampus_3months.txt.gz |
2.5 Mb |
(ftp)(http) |
TXT |
| GSE90693_normalizedFPKM_TPR50_Hippocampus_6months.txt.gz |
1.8 Mb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
| Processed data are available on Series record |
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