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| Status |
Public on Jan 30, 2017 |
| Title |
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
EMT, Epithelial to mesenchymal transition is a developmental biology process associated with migration, known to be involved in cancer metastasis. To study this process, we used the breast epithelial cell line MCF10A that enter in EMT after treatment with the cytokine TGFB or by expression of EMT transcriptor factor SNAIL.
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| Overall design |
mRNA profiles of MCF10A cells treated for 1 or 6 days with TGFb (done in duplicate), and mRNA profiles of Snail inducible line, MCF10A-SNAIl, induced for 1 or 6 days.
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| Contributor(s) |
Valentine C, Maheswaran S, Ting D, Sil S, Morris R |
| Citation(s) |
27926867 |
| |
| Submission date |
Oct 25, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Robert Morris |
| E-mail(s) |
morris.robert@mgh.harvard.edu
|
| Phone |
617-724-6552
|
| Organization name |
Mass. General Hospital Cancer Center
|
| Street address |
149 13th Street
|
| City |
Charlestown |
| State/province |
Massachusetts |
| ZIP/Postal code |
02129 |
| Country |
USA |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA350495 |
| SRA |
SRP092049 |
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