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| Status |
Public on Dec 21, 2017 |
| Title |
Comprehensive DNA Microarray Analysis for the Gene Sets Involved in Allergic Reaction by Allergic Effector Cells |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Mast cells, basophils, and eosinophils play an important role in allergic disorders as effector cells. These cells secrete abundant serine proteases as well as chemical mediators and cytokines. Various serine proteases including SLPI are also important for to regulate an allergic response in these effector cells, although the expression profiles and functions of these proteases still remain unclear.
We carried out DNA microarrays to clarify the role of SLPI in allergic responses.
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| Overall design |
Total RNAs were isolated from each allergic effector cells derived from bone marrow cells of wild type or SLPI deficient mice. Hybridized Affymetrix GeneChip was scanned and the data was analyzed.
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| Contributor(s) |
Yabe-Wada T, Sato T, Matsuba S |
| Citation(s) |
29181004 |
| |
| Submission date |
Oct 05, 2016 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Toshiki Yabe-Wada |
| E-mail(s) |
tyw5510@kanazawa-med.ac.jp
|
| Phone |
762188121
|
| Organization name |
Kanazawa Medical University
|
| Department |
School of Medicine
|
| Lab |
Department of Immunology
|
| Street address |
1-1 Daigaku
|
| City |
Uchinada Kahoku |
| State/province |
Ishikawa |
| ZIP/Postal code |
920-0293 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA345467 |
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