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Series GSE87565 Query DataSets for GSE87565
Status Public on Dec 15, 2016
Title High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary In this setup we have used RNA-seq, DHS-seq, and H3K27ac ChIP-seq to identify changes in transcription, chromatin landscape and enhancer activity in livers of mice fed a high fat diet (HFD) and mice returned from HFD to Chow.
Overall design Global gene expression analysis, DHS-seq and H3K27ac ChIP-seq in livers of 7 week old mice fed chow or HFD. Furthermore, we have performed global gene expression analysis and H3K27ac ChIP-seq in 12 week old mice initially fed HFD then returned to chow or continued chow diet.
Contributor(s) Siersbæk M, Varticovski L, Yang S, Baek S, Nielsen R, Mandrup S, L Hager G, H Chung J, Grøntved L
Citation(s) 28071704
Submission date Oct 03, 2016
Last update date May 15, 2019
Contact name Lars Grøntved
Phone +45 24 60 14 06
Organization name University of Southern Denmark
Department Biochemistry and Molecular Biology
Street address Campusvej 55
City Odense
ZIP/Postal code 5230
Country Denmark
Platforms (1)
GPL18480 Illumina HiSeq 1500 (Mus musculus)
Samples (28)
GSM2333833 Chow, rep1 (RNA-Seq)
GSM2333834 Chow, rep2 (RNA-Seq)
GSM2333835 Chow, rep3 (RNA-Seq)
BioProject PRJNA345270
SRA SRP090817

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE87565_RAW.tar 674.9 Mb (http)(custom) TAR (of BEDGRAPH)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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