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| Status |
Public on Feb 28, 2017 |
| Title |
Influence of Anti-VEGFA and dexamathasone treatments on the early phase of cornea angiogenesis |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
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| Summary |
Inflammation is a key component of pathological angiogenesis. Here we monitor gene expression profiles of the pre-sprouting phase of corneal angiogenesis in the rat model, as influenced by topically applied treatments.
We used GeneChip Rat Genome 230 2.0 Array to monitor gene expression profies of several genes in the different treatment groups
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| Overall design |
Animals were sutured as a stimuli for neovascularisation, and treatments (anti-VEGFA, goat IgG and dexamethasone) given topically to module the early response. Eyedrops were given four times per day, for two days.
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| Contributor(s) |
Mukwaya A, Mirabelli P, Xeroudaki M, Peebo BB, Lennikov A, Lagali N |
| Citation(s) |
28811496 |
| |
| Submission date |
Sep 25, 2016 |
| Last update date |
Oct 13, 2017 |
| Contact name |
Neil Lagali |
| Organization name |
linkoping University
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| Department |
Ophthalmology
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| Street address |
sandbacksgatan 7
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| City |
Linkoping |
| ZIP/Postal code |
SE-581 83 |
| Country |
Sweden |
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| Platforms (1) |
| GPL1355 |
[Rat230_2] Affymetrix Rat Genome 230 2.0 Array |
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| Samples (16)
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| Relations |
| BioProject |
PRJNA344417 |
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