|
| Status |
Public on Sep 15, 2016 |
| Title |
In vivo correction of anemia in thalassemic mice by gammaPNA-mediated gene editing with stem cell factor treatment and nanoparticle delivery |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
CD117+ (c KIT) and CD117- cells were isolated from mouse bone marrow and there gene expression profile was performed to observe up regulation as well as down regulation of genes. It has been noticed that CD117+ cells has many upregaulted DNA repair genes as compare to cd117- population.
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| |
|
| Overall design |
Total RNA obtained from isolated CD117+ and CD117- cells from transgenic mice bone marrow
|
| |
|
| Contributor(s) |
Glazer PM, Bahal R |
| Citation(s) |
27782131 |
| |
| Submission date |
Sep 13, 2016 |
| Last update date |
Nov 24, 2017 |
| Contact name |
Francesc Lopez |
| E-mail(s) |
francesc.lopez@yale.edu
|
| Organization name |
Yale University
|
| Department |
Department of Genetics
|
| Lab |
YCGA
|
| Street address |
P.O. Box 27386
|
| City |
West Haven |
| State/province |
CT |
| ZIP/Postal code |
06516 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17543 |
Illumina MouseWG-6 v2.0 R2 expression beadchip |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA342793 |
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