|
| Status |
Public on Nov 01, 2017 |
| Title |
The Transgenerational Effects of Prenatal Synthetic Glucocorticoids |
| Organism |
Cavia porcellus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
First generation animals (F1) were exposed to multiple courses of synthetic glucocorticoids in utero. Animals were then bred to produce second (F2) and third (F3) generation offspring. These animals underwent behavioural assessmenets before sacrifice. In this experiment the paraventricular nucleus of the hypothalamus fo F1, F2, and F3 female anmials (Beta and Control) have been extracted via micro-punch and RNA has been extracted.
|
| |
|
| Overall design |
F1 Control n=5 vs F1 Beta n=5, F2 Control n=5 vs F2 Beta n=5, F3 Control n=6 vs F3 Beta n=6
|
| |
|
| Contributor(s) |
Moisiadis VG, Constantinof A, Szyf M, Matthews SG |
| Citation(s) |
28924262 |
| |
| Submission date |
Aug 18, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Stephen Matthews |
| Organization name |
University of Toronto
|
| Street address |
1 King's College Circle
|
| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5S1A8 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL22346 |
Illumina HiSeq 2500 (Cavia porcellus) |
|
| Samples (34)
|
|
| Relations |
| BioProject |
PRJNA339489 |
| SRA |
SRP082393 |
Less...
More...