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Status |
Public on Sep 01, 2016 |
Title |
Analysis of transcriptomes of naive CD4+ T cells, polarized under Th17 cell skewing conditions for 24h in presence or abscence of CK2 Inhibitor |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
The goal of this study was to elucidate the transcriptional changes evoked by CK2 inhibition in developing Th17 cells
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Overall design |
Messenger RNA profiles of naive CD4+ T cells, FACS-purifed from spleens of C57BL6 mice and stimulated with plate-bound anti-CD3 and anti-CD28 for 24h under Th17 polarizing conditions in presence or abscence of CK2 inhbititors DMAT (1.5µM) or CX4945 (1µM) were generated by sequencing using Illumina MiSeq
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Contributor(s) |
Ulges A, Bopp T |
Citation(s) |
27555590 |
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Submission date |
Aug 11, 2016 |
Last update date |
May 15, 2019 |
Contact name |
Tobias Bopp |
Organization name |
University Medical Center Mainz
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Department |
Institute for Immunology
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Street address |
Langenbeckstrasse 1
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City |
Mainz |
ZIP/Postal code |
55131 |
Country |
Germany |
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Platforms (1) |
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Samples (4)
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Relations |
BioProject |
PRJNA338619 |
SRA |
SRP081279 |