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Series GSE85311 Query DataSets for GSE85311
Status Public on Oct 01, 2020
Title Epigenetic patterns with aging and exercise are associated with indicators of healthspan in humans
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Genome wise DNA methylation profiling of peripheral blood mononuclear cells (PBMCs) obtained from younger sedentary (Y-SED), older sedentary (O-SED) and older aerobically exercise trained (O-Ex) human subjects. The Illumina 450K methylation beadchip array was used to obtain DNA methylation profiles across approximately 450,000 CpG dinucleotide methylation loci in DNA isolated from PBMCs. Samples include 12 Y-SED subjects, 15 O-SED subjects and 11 O-Ex subjects.
 
Overall design DNA methylation was assessed in peripheral blood mononuclear cells (PBMCs) of 12 young-sedentary (Y-SED), 15 older-sedentary (O-SED) and 11 older exercise trained (O-Ex) individuals using the Illumina HumanMethylation 450K array.
 
Contributor(s) Martens CR, Lubieniecki KL, McNamara MN, Bohr AD, McQueen MB, Seals DR
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Submission date Aug 08, 2016
Last update date Oct 02, 2020
Contact name Christopher R Martens
E-mail(s) christopher.martens@colorado.edu
Organization name University of Colorado Boulder
Department Integrative Physiology
Lab Integrative Physiology of Aging Laboratory
Street address 354 UCB
City Boulder
State/province CO
ZIP/Postal code 80309
Country USA
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (38)
GSM2264517 genomic DNA from young PBMCs 1
GSM2264518 genomic DNA from young PBMCs 2
GSM2264519 genomic DNA from young PBMCs 3
Relations
BioProject PRJNA338153

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE85311_RAW.tar 183.1 Mb (http)(custom) TAR
GSE85311_Unmethylated_and_methylated_signal_intensities.csv.gz 101.9 Mb (ftp)(http) CSV
Processed data included within Sample table

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