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| Status |
Public on May 15, 2019 |
| Title |
Tobacco-related alterations in airway gene expression are rapidly reversed within weeks following smoking cessation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
RNA was obtained longitudinally from normal nasal epithelium of smokers who have quit smoking over 6 months period. Statistical analysis of gene expression data identified genes differentially expressed with short-term smoking cessation and categorized the kinetics of of these genes in different biological functions with different dynamics following smoking cessation.
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| Overall design |
Affymetrix GeneST arrays were run on total RNA obtained nasal epithelial brushings of 8 active smokers enrolled in smoking-cessation programs. Brushings were obtained at baseline and at 4, 8, 16, and 24-weeks after smoking-cessation (n=33). Replicates are excluded.
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| |
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| Contributor(s) |
Hijazi K, Spira A |
| Citation(s) |
31061400 |
| |
| Submission date |
Jun 14, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Kahkeshan Hijazi |
| E-mail(s) |
khijazi@bu.edu
|
| Phone |
+16173099896
|
| Organization name |
Boston University
|
| Lab |
Computational Biomedicine
|
| Street address |
715 Albany Street
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02118 |
| Country |
USA |
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| Platforms (1) |
| GPL15034 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [HuGene10stv1_Hs_ENTREZ, Brainarray v14] |
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| Samples (33)
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| Relations |
| BioProject |
PRJNA325675 |
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