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| Status |
Public on Aug 15, 2016 |
| Title |
Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy (mRNA) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). In this study, we analyzed DNA methylomes (Infinium 450K HumanMethylation BeadChip) and transcriptomes (Infinium HT-12 v4) to characterize differentially methylated probes (DMPs) and differentially expressed genes (DEGs) between the left and right ventricles of human DCM.
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| |
|
| Overall design |
Illumina 450K array and HT-12 v4 array for the left, right ventricles
|
| |
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| Contributor(s) |
Jo B, Koh I, Bae J, Yu H, Jeon E, Lee H, Kim J, Choi M, Choi S |
| Citation(s) |
27417303, 27699191 |
| |
| Submission date |
May 11, 2016 |
| Last update date |
Jun 27, 2019 |
| Contact name |
Bong-seok Jo |
| Organization name |
Kangwon national university
|
| Street address |
Kangwon university street 1
|
| City |
Chuncheon |
| ZIP/Postal code |
200-701 |
| Country |
South Korea |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (30)
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| This SubSeries is part of SuperSeries: |
| GSE81339 |
Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy |
|
| Relations |
| BioProject |
PRJNA321318 |
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