|
| Status |
Public on Jan 03, 2017 |
| Title |
RNA-Sequencing to identify the transcriptional targets of Rai1 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The goals of this study are to harvest Rai1-deficient mouse brains from multiple tissues and timepoints and compare the transcriptome with their wild-type littermates.
Methods: mRNA profiles from Rai1 conditional knockouts and wild-type mice were generated by deep sequencing, in duplicate using Illumina system.
Conclusions: Our study suggests that Rai1 preferentially regulate genes involved in cell adhesion and neural projection.
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| |
|
| Overall design |
Cortical, striatal, and hypothalamic mRNA profiles of wild-type and Rai1 conditional knockout mice were generated by deep sequencing, in duplicates.
|
| |
|
| Contributor(s) |
Huang W, Xu J, Luo L |
| Citation(s) |
27693255 |
| |
| Submission date |
May 06, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Liqun Luo |
| E-mail(s) |
lluo@stanford.edu
|
| Phone |
(650) 723-6645
|
| Organization name |
Stanford University
|
| Department |
Department of Biological Sciences
|
| Lab |
Luo Lab
|
| Street address |
Herrin Labs, Rooms 152 and 154
|
| City |
Stanford |
| ZIP/Postal code |
94305 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (16)
|
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| This SubSeries is part of SuperSeries: |
| GSE81207 |
Integrating Molecular and Organismal Analyses of Rai1, The Causal Gene for Smith-Magenis Syndrome |
|
| Relations |
| BioProject |
PRJNA320889 |
| SRA |
SRP074487 |
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