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Status |
Public on Mar 23, 2017 |
Title |
Comparison of gene expression in control bam-Gal4 and control undriven tbrd-2RNAi Drosophila testes with tbrd-2 knockdown testes |
Organism |
Drosophila melanogaster |
Experiment type |
Expression profiling by array
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Summary |
Gene expression is tightly linked to histone acetylation on lysine residues that can be recognized by bromodomains. The testis-specific bromodomain protein tBRD-2 is essential for male fertility, interacts with tBRD-1 and might act as a co-factor of testis-specifc TAFs. Here, we perform microarray analyses and demonstrate that tBRD-2 selectively controls gene expression in male germ cells.
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Overall design |
Testes were dissected from 0-2 day old Drosophila males. The control samples were bam-Gal4 and undriven tbrd-2 RNAi. In addition testes from tbrd-2 knockdown males were used.
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Contributor(s) |
Rathke C, Bartkuhn M |
Citation(s) |
28235844 |
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Submission date |
May 02, 2016 |
Last update date |
Jul 11, 2019 |
Contact name |
Marek Bartkuhn |
E-mail(s) |
marek.bartkuhn@gen.bio.uni-giessen.de
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Organization name |
Justus-Liebig-University Giessen
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Department |
Biomedical Informatics and Systems Medicine
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Street address |
Aulweg 132
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City |
Giessen |
State/province |
Hessen |
ZIP/Postal code |
35392 |
Country |
Germany |
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Platforms (1) |
GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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Samples (9)
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Relations |
BioProject |
PRJNA320296 |