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| Status |
Public on Jun 06, 2008 |
| Title |
Expression data from human mesenchymal stem cells (six batches) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Human mesenchymal stem cells (hMSCs), which are multipotent cells to differentiate into several cell types, are expected to be a useful tool for cellular therapy. In some clinical settings, hMSCs have immuno-suppressive effects for GVHD (Graft-versus-host disease) and are expanded in vitro before application. To find biomarkers that indicate the culture stage of hMSCs, we performed microarray analysis for hMSCs derived from bone marrow, using Affymetrix GeneChip Human Genome U133 Plus 2.0 (54,613 probe sets).
Keywords: mesenchymal stem cells, culture stage
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| Overall design |
We profiled the gene expression in 6 different batches of hMSCs. The cells were cultured and subjected to total RNA extraction. We performed microarray analysis using 6 batches provided by 6 different individuals in early stage (passage #4 or 5), middle stage (#7 or 9) or senescing stage (#22, 24, or 28).
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| Contributor(s) |
Tanabe S, Sato Y, Suzuki T, Suzuki K, Nagao T, Yamaguchi T |
| Citation(s) |
18550633, 24728500, 27928465, 25621121 |
| Submission date |
May 24, 2007 |
| Last update date |
Aug 16, 2019 |
| Contact name |
Shihori Tanabe |
| Organization name |
National Institute of Health Sciences
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| Department |
Division of Risk Assessment
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| Street address |
3-25-26, Tonomachi, Kawasaki-ku
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| City |
Kawasaki |
| State/province |
Kanagawa |
| ZIP/Postal code |
210-9501 |
| Country |
Japan |
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| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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| Samples (23)
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| GSM194075 |
mesenchymal stem cells, lot#4F1127, 4th passage |
| GSM194076 |
mesenchymal stem cells, lot#4F0312, 4th passage |
| GSM194077 |
mesenchymal stem cells, lot#5F0138, 4th passage |
| GSM194078 |
mesenchymal stem cells, lot#4F0591, 4th passage |
| GSM194079 |
mesenchymal stem cells, lot#4F0760, 4th passage |
| GSM194080 |
mesenchymal stem cells, lot#4F1560, 5th passage |
| GSM194081 |
mesenchymal stem cells, lot#4F1127, 7th passage |
| GSM194082 |
mesenchymal stem cells, lot#4F0312, 7th passage |
| GSM194083 |
mesenchymal stem cells, lot#5F0138, 7th passage |
| GSM194084 |
mesenchymal stem cells, lot#4F1560, 7th passage |
| GSM194085 |
mesenchymal stem cells, lot#4F0591, 7th passage |
| GSM194086 |
mesenchymal stem cells, lot#4F1127, 9th passage |
| GSM194087 |
mesenchymal stem cells, lot#4F0312, 9th passage |
| GSM194088 |
mesenchymal stem cells, lot#5F0138, 9th passage |
| GSM194089 |
mesenchymal stem cells, lot#4F1560, 9th passage |
| GSM194090 |
mesenchymal stem cells, lot#4F0591, 9th passage |
| GSM194091 |
mesenchymal stem cells, lot#4F0760, 9th passage |
| GSM194092 |
mesenchymal stem cells, lot#4F1127, 22nd passage |
| GSM194093 |
mesenchymal stem cells, lot#5F0138, 24th passage |
| GSM194094 |
mesenchymal stem cells, lot#4F0312, 28th passage |
| GSM194095 |
mesenchymal stem cells, lot#4F1560, 28th passage |
| GSM194096 |
mesenchymal stem cells, lot#4F0591, 28th passage |
| GSM194097 |
mesenchymal stem cells, lot#4F0760, 28th passage |
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| Relations |
| BioProject |
PRJNA99927 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE7888_RAW.tar |
114.0 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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