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Series GSE78849 Query DataSets for GSE78849
Status Public on Sep 27, 2016
Title Investigation of the effect of succinate and dimethyl malonate on murine bone-marrow derived macrophages (BMDMs) treated with or without LPS
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We aim to further elucidate the effect of succinate and the succinate dehydrogenase inhibtor, dimethyl malonate, on macrophages treated with LPS. Specifically we want to deepen our understanding of how these reagents influence both LPS-induced IL-1B and IL-10.
Overall design BMDMs were either left untreated or treated with succinate or dimethyl malonate for 3 h prior to treatment with or without LPS for 4 or 48 h.
Contributor(s) Mills E, O'Neill L, Varma M, Li B, Xavier R, Latorre I
Citation(s) 27667687
Submission date Mar 02, 2016
Last update date May 15, 2019
Contact name Mukund Varma
Organization name Broad Institute
Street address 415 Main Street
City Cambridge
State/province MA
ZIP/Postal code 02139
Country USA
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (21)
GSM2079451 C1A
GSM2079452 S1A
GSM2079453 D1A
BioProject PRJNA314136
SRA SRP071087

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Supplementary file Size Download File type/resource 391.3 Kb (ftp)(http) TXT
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