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| Status |
Public on Feb 29, 2016 |
| Title |
Global gene expression changes during immune complex-induced neutrophil activation (wild type and Card9‒/‒ cells) |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
--- Raw data of the Supplementary Table 1 of the Nature Communications article 'Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo'
We used microarray to obtain global gene expression data of immobilised immune complex-activated mouse neutrophils in the presence and absence of the gene expression regulator molecule CARD9.
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| Overall design |
Mouse neutrophils were isolated from the bone marrow and were plated on human serum albumin & anti-human serum albumin antibody-coated surfaces at a 4 x 106 cell concentration. Human serum albumin-coated surfaces served as controls. The cells were stimulated for 4 hours before RNA preparation. The experiments were done at 3 independent timepoints.
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| Contributor(s) |
Németh T, Futosi K, Sitaru C, Ruland J, Mócsai A |
| Citation(s) |
27032818 |
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| Submission date |
Feb 18, 2016 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Attila Mocsai |
| E-mail(s) |
mocsai@eok.sote.hu
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| Organization name |
Semmelweis University
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| Department |
Department of Physiology
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| Street address |
Tuzolto utca 37-47
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| City |
Budapest |
| ZIP/Postal code |
1094 |
| Country |
Hungary |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA312518 |
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