|
| Status |
Public on Dec 06, 2016 |
| Title |
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
Here we analyze histone modifications and transcriptome profiles of EZH2-deficient human embroynic stem cells
|
| |
|
| Overall design |
Histone modifications (H3K27me3, H3K4me3, H3K27ac and H3K4me1) and transcriptome (mRNA-Seq) from EZH2-/- (Null), Ezh2-/- +EZH2 (Null + EZH2), Ezh2 -/+ (Het) and EZH2 +/+ (WT) human ESC
|
| |
|
| Contributor(s) |
Collinson A, Rugg-Gunn P |
| Citation(s) |
27926872 |
| |
| Submission date |
Jan 07, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Felix Krueger |
| E-mail(s) |
fkrueger@altoslabs.com
|
| Organization name |
Altos Labs
|
| Department |
Bioinformatics
|
| Street address |
Granta Park
|
| City |
Cambridge |
| ZIP/Postal code |
CB21 6GP |
| Country |
United Kingdom |
| |
|
| Platforms (2) |
| GPL15433 |
Illumina HiSeq 1000 (Homo sapiens) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (33)
|
|
| This SubSeries is part of SuperSeries: |
| GSE81674 |
Characterisation of EZH2-deficient human embryonic stem cells |
|
| Relations |
| BioProject |
PRJNA308197 |
| SRA |
SRP068192 |
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