|
| Status |
Public on Jan 04, 2017 |
| Title |
Cooperative Associations with Sites on Different Nucleosomes Mediate Heterochromatin Spreading |
| Organism |
Saccharomyces cerevisiae |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Sir3wH and Sir4CC are required for SIR complex spreading in vivo but play partially redundant roles when Sir3 is overexpressed.
|
| |
|
| Overall design |
ChIP-seq analysis of Sir3 chromatin binding and its dependence on Sir3wH domain deletion and Sir4-I1311N mutation.
|
| |
|
| Contributor(s) |
Lu C, Jih GT, Moazed D |
| Citation(s) |
27835568 |
| |
| Submission date |
Jan 05, 2016 |
| Last update date |
May 15, 2019 |
| Contact name |
Gloria Jih |
| E-mail(s) |
glowjih@gmail.com
|
| Organization name |
Harvard Medical School
|
| Department |
Cell Biology
|
| Lab |
Danesh Moazed
|
| Street address |
240 Longwood Ave, LHRRB 517
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17342 |
Illumina HiSeq 2500 (Saccharomyces cerevisiae) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA307702 |
| SRA |
SRP068104 |
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