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Series GSE75997 Query DataSets for GSE75997
Status Public on Dec 11, 2016
Title Gene expression changes upon Mll1 knockout in NUP98-HOXA9 transformed murine LSKs
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report Illumina next generation RNA sequencing (RNAseq) of NUP98-HOXA9 in vitro transformed murine LSKs upon genetic deletion of Mll1. These gene expression data illustrate that Mll1 regulates Hoxa, Hoxb and Meis1 expression in NUP98-HOXA9 transformed murine BM cells.
 
Overall design RNAseq comparing Mll1 homozygous knockout cells to Mll1 flox/flox control
 
Contributor(s) Armstrong SA, Xu H
Citation(s) 27889185
Submission date Dec 14, 2015
Last update date May 15, 2019
Contact name Scott Armstrong
Organization name Memorial Sloan-Kettering Cancer Center
Street address 1275 York Avenue
City New York
ZIP/Postal code 10065
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (6)
GSM1971634 MLL1ff_4OHT_1
GSM1971635 MLL1ff_4OHT_2
GSM1971636 MLL1ff_4OHT_3
Relations
BioProject PRJNA305926
SRA SRP067361

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE75997_RAW.tar 1.5 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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