|
| Status |
Public on Nov 29, 2016 |
| Title |
Activation of the IGF1 pathway mediates changes in cellular contractility and motility in single-suture craniosynostosis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We examined the effect pg IGF1 actibation on cellular contractility and migration in SSC osteoblast cells. Based on microarray levels of IGF1 expression, we selected fifteen cases and nine controls spanning from the highest IGF1 expression to the lowest in cases and controls. Subsequently, the pattern of IGF1 expressions in these cells was assessed using high throughput RNA sequencing.
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| |
|
| Overall design |
RNA-seq based gene expression profiling of fifteen SSC osteoblasts and nine control osteoblasts.
|
| |
|
| Contributor(s) |
Wheeler MM, Frazar C, Smith JD |
| Citation(s) |
26659664 |
| |
| Submission date |
Nov 30, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Nathan J. Sniadecki |
| E-mail(s) |
nsniadec@uw.edu
|
| Organization name |
University of Washington
|
| Lab |
Nathan Sniadecki
|
| Street address |
Box 352600, Mechanical Engineeering
|
| City |
Seattle |
| State/province |
Washington |
| ZIP/Postal code |
98195 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (24)
|
|
| Relations |
| BioProject |
PRJNA304465 |
| SRA |
SRP066818 |
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